Toxicology for the Scientist
Risk of chemical exposure is something we deal with every day, whether it is environmental, dietary, or medicinal exposure. The foundation upon which human health risk assessment, ecological risk assessment, and product safety testing are based is Toxicology. Therefore chemists and scientists from a range of sectors and disciplines can benefit professionally by increasing their understanding of fundamental Toxicology.
Join Sci-Mind® and dive into the key steps of conducting risk assessment. Cohort session activities will allow you to gain hands-on practice in risk assessment, and direct feedback from experts will provide you with valuable information from a variety of expert perspectives.
Spotlight On: Introduction to Toxicology
Chemicals are all around us. They are the air we breathe, the water we drink, the food we eat, and the medicines we take. We are exposed to chemicals at the workplace, at home, and at places in between, some are man made like pesticides or car exhaust. As scientists we play the role of toxicologists. We ask such questions as: How does exposure to chemicals affect our health or that of our environment? Are all chemicals hazardous? How do I judge the risk of exposure?
Join Sci-Mind® and Toxicology for the Scientist to better understand the principles of Toxicology and applied hazard assessment. Our chemists and scientists come from a wide-range of sectors and disciplines and have benefited professionally by assessing real-world situations chemical hazards affecting human health, ecology, or product safety. The cohort session activities allow learners hands-on practice in hazard assessment and receive feedback from an interdisciplinary team of subject matter experts (SMEs) in fields such as industrial product safety, analytical chemistry, clinical pharmaceutical research, public health, and forensic science. This experience should benefit those scientists working with hazardous chemicals in industry, academia, or government, along with those who are interested in Toxicology and regulations.
Over six weeks, learners are able to differentiate between hazard and risk assessment, identify biological mechanisms of exposure, and examine endpoints of concern. In addition, learners are a part of an online community to discuss their research and applicable regulations in the field. There is a short research project. Specifically, learners will:
- Examine toxicological hazard assessment for chemicals
- Compare acute and chronic exposure scenarios
- Examine key toxicity pathways for human health endpoints
- Analyze dose-response relationships
- Assess uncertainties of risk estimates per regulatory guidelines, standards & regulations
Who Should Attend?
Toxicology for the Scientist is for chemists and scientists working across the chemical enterprise or environmental professionals who have a solid understanding of chemistry. Previous participants represent job functions such as analytical chemists, forensic scientists, clinical biologists and medical researchers, food and cosmetic scientists, environmental consultants, industrial hygienists, regulatory professionals.
Below is an outline of topics for the six-week cohort. Each week has measurable learning objectives and will present the learner with technical readings, interactive knowledge checks, assignments, and discussion postings. In addition, each week has a LIVE interactive session with one or more SME.
- Week 1: Introductions & Hazard Identification This week you will identify terms in Toxicology. You will differentiate concepts of risk assessment and hazard identification.
- Week 2: Exposure Assessment & Online Databases This week you will examine exposure characteristics of a hazardous chemical. You will evaluate exposure by population type using online resources.
- Week 3: Human Health Endpoints, Toxicokinetics, Toxicodynamics & Online Tools This week you will apply ADM model to a hazardous chemical. You will explore toxicological effects of a chemical hazard on biological endpoints. You will examine toxicity methods using online tools. You will review assays and published toxicological studies.
- Week 4: Dose-Response This week you will interpret dose-response relationships for a hazardous chemical.
- Week 5: Risk Estimates & Regulations This week you will compare uncertainties of different risk estimates for a hazardous chemical. You will illustrate exposure scenarios for a select human population associated with a risk estimate.
- Week 6: Learner Presentations You will communicate your findings for a chemical hazard. You will justify a course of action.
Customizable Learning Compounds
Prior to the first cohort session, each learner will receive a 1-1 consultation with a Sci-Mind® curriculum developer who will develop and customize his or her own personal learning solution. Possible topics are:
- ADME & Toxicity Pathways
- Endpoints of Concern
- Cheminformatics: QSAR Models, Data Mining, in silico
- Environmental Persistence of Chemicals
- Bioaccumulation of Chemicals in Organisms
- Testing for Ecological Toxicity
- Clinical Toxicology Testing
- Forensics Toxicology
- Risk Perception & Uncertainty in Toxicology
- Hazard Communication
- Sustainability Alternative Assessments across Product/Material Life Cycle
Meet our Experts
We couldn’t be more thrilled with the amazing support and enthusiasm we’ve received from professionals all over the scientific community. Subject Matter Experts (SMEs) are a critical part of the Sci-Mind® experience and educational model. Ranging from a span of industrial sectors, they provide insight and guidance during content development, but also offer years of expertise via informal interaction within the community.
PhD, Universirty of South Florida
PhD, DABT (INND)
PhD, University of North Carolina
PhD, The Dow Chemical Company
PhD, University of South Florida
PhD, Science and Technology Policy Institute
|A. Phil Leber
PhD, DABT, Environmental Health Decisions
PhD, The Dow Chemical Company
National Library of Medicine
MFS, FTS-ABFT, DC OCME
|Sabra R. Botch-Jones
MS, MA, FTS-ABFT
If you are interested in becoming involved in Sci-Mind® as a content contributor or subject matter expert, please contact us.