The 21st century high school chemistry classroom provides a dynamic learning environment that is student centered and curriculum-driven. The floor plan is designed for conversation, collaboration, and discovery. The classroom should contain multiple spaces that provide for long-term multidisciplinary projects, individual and small group learning, inquiry lessons, project-based learning, and problem solving. Flexibility in the arrangement of space, which includes movable workstations, is highly recommended. Universal design allows students with disabilities to fully participate and have access to all facilities, technology, and safety equipment.