Molecule of the Week

Anabasine

December 29, 2008

Anabasine [(±)-3-(2-piperidinyl)pyridine] is a pyridine alkaloid, closely related to nicotine. It has been used historically as an insecticide. Its isolation from the shrub Anabasis aphylla L. was reported by A. P. Orekhov and G. P. Men’shikov in 1931. Anabasine is also a nicotinic acetylcholine receptor agonist, and, in high doses, can cause symptoms similar to those of nicotine poisoning.

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