Molecule of the Week
March 8, 2010
Benzoic anhydride is prepared by heating benzoic acid with acetic anhydride in the presence of H3PO4, as described by H. T. Clarke and E. J. Rahrs in 1923 in volume 3 of Organic Syntheses. It is used primarily as a benzoylating agent in industrial chemical synthesis. Recently, D. Seidel and co-workers used benzoic anhydride and other inexpensive reagents in acylation reactions to give products that can be enantiomerically resolved.
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