Molecule of the week

Birinapant

July 1, 2013

Birinapant is a developmental drug that is designed to restore the apoptosis functionality (programmed cell death) to cancer cells. The unusual dimeric molecule inhibits proteins that block apoptosis. TetraLogic Pharmaceuticals in Malvern, PA, is currently in early phase II clinical trials for using birinapant in leukemia, pancreatic cancer, and ovarian cancer patients.

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Rendering of the Birinapant molecule.