Molecule of the Week

Cubane

March 10, 2008

The highly symmetrical C8H8 hydrocarbon cubane was first synthesized by Philip Eaton in 1964. Before that, many thought that it could not be synthesized because of the great strain generated by its 90° C–C–C bond angles. Cubane is isomeric with cyclooctatetraene, and this relationship has been used to synthesize cyclooctatetraenophanes from cubane-derivative building blocks.