Molecule of the Week

Cycloguanil

May 26, 2008

Cycloguanil was first observed in 1951 as a metabolite of the antimalarial drug chlorguanide; it also has shown activity against malaria. Because traditional antimalarials are becoming ineffective against new strains of the malarial protozoan Plasmodium falciparum, renewed efforts are underway to develop cycloguanil into a commercial drug.