Molecule of the Week

Dabigatran etexilate

November 15, 2010

Dabigatran etexilate is an anticoagulant drug developed and marketed by Boehringer Ingelheim. The parent compound, dabigatran, is a potent thrombin blocker, but it cannot be administered orally. Adding the hydrophobic carbohexoxy group (“etexilate”) to the imine nitrogen created an orally absorbable prodrug.

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