Molecule of the Week

(DHQD)2PHAL

March 16, 2009

Hydroquinidine 1,4-phthalazinediyl diether, commonly abbreviated as (DHQD)2PHAL, is a widely used ligand for the Sharpless asymmetric dihydroxylation reaction. Nobel Prize–winning (2001) chemist K. Barry Sharpless and coauthors reviewed its use in 1994. It is sold by Sigma-Aldrich–Fluka.


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