Molecule of the Week


February 2, 2009

First prepared by Pfeiffer and Sauvage in 1904, triphenylphosphine’s first important use in organic synthesis was in the Wittig reaction (1954) that converts aldehydes and ketones to alkenes. Triphenylphosphine is also used in the Suzuki, Mitsunobu, and Appel reactions, and as a transition-metal ligand in olefin polymerizations.