The interface between a Biologist and Medicinal Chemist are at the heart of a drug discovery program and it is critical that there be mutual understanding of the different disciplines involved. Pharmacology is the chemical control of physiology, but how can physiology be expressed in chemical terms?
When drugs interact with living systems they can present different profiles of activity in the body. Join Terry Kenakin, Professor of Pharmacology at the UNC School of Medicine as he illustrates how Pharmacology uses descriptive and predictive data to extend the snapshot of activity for a drug in a test system with scales that can predict drug activity in a full range of physiological systems. Register now to learn the basics of the drug discovery process and the key issues of system-independent properties like efficacy and affinity, in making a therapeutic drug that can better guide molecule candidate selection and reduce attrition.
This ACS Webinar is moderated by Bryan Tweedy of the American Chemical Society and co-produced by the ACS Office of Career and Professional Education.
What You Will Learn
- How chemicals affect physiology and the properties that are required to modify drug efficacy and affinity
- How the data coming from pharmacological assays are used for structure-activity modification
- The current landscape of drug targets and the process of how to validate those targets for therapeutic advantage and how the mechanisms of actions of various drugs uniquely modify according to disease
Additional Resources
- Pharmacology for Chemists - ACS Institute Online 6 Session Course that will teach you the fundamentals of pharmacology to inform your work in the drug development industry, whether you are collaborating with other scientists, managing projects, or moving into a new area of research.
Co-Produced With
What an attendee said about this ACS Webinar!
This webinar has allowed me to see the process of a medicinal chemist from another point of view, as well as to create awareness of something as important as the interpretation of data.
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