Fighting Cancer: Targeting CNS Malignancy with Kinase Inhibitors

January 26, 2017
Session 1 of the 2017 Drug Design and Delivery Symposium


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Delivering compounds to the brain can be difficult. Join us as Timothy P. Heffron begins our module on fighting cancer with a discussion on the unmet need for neurooncology treatments, the significant opportunities that remain for new kinase inhibitors in this space and the unique challenges and considerations for brain-penentrant kinase inhibitor programs.

What You Will Learn

  • Free brain penetration (as opposed to just brain penetration) must be considered by neurooncology programs
  • Kinase inhibitors are of interest for the treatment of both primary brain tumors and brain metastases.
  • Focused drug discovery efforts, including optimization of physicochemical properties, can yield freely brain penetrating kinase inhibitors.

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The Fine Print

ACS Webinars® does not endorse any products or services. The views expressed in this presentation are those of the presenters and do not necessarily reflect the views or policies of the American Chemical Society.

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Experts

Mark Wittman
Bristol-Myers Squibb 

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