Passive diffusion plays an essential role in oral absorption of drugs through the gastrointestinal tract, penetration across the blood-brain barrier to reach Central Nervous System disease targets, entry into hepatocytes to be metabolized, and drug reabsorption from renal tubules. Passive diffusion and transporters coexist to affect drug disposition.
Join Research Fellow Li Di of Pfizer during this free interactive broadcast as she discusses why design principles that increase passive permeability are effective approaches to increase oral bioavailability, enhance brain penetration, and reduce renal clearance.
What You Will Learn
- The critical role of passive permeability in drug design
- How physicochemical properties influence passive permeability
- How passive permeability and transporters coexist to affect ADME properties of drugs
- Thursday, March 19, 2020 2-3pm ET
- Fee: Free to Attend
- Download speaker slides the day of the Live event