Rational Design of Small Molecules Targeting RNA
There is much interest in developing small molecules that target RNA for lead therapeutic and chemical probe purposes. Join Matt Disney of The Scripps Research Institute as he describe efforts to obtain such compounds to help decipher the varied roles of RNA in disease biology.
What You Will Learn
- General issues in developing chemical probes and lead therapeutic small molecules directed towards RNA
- Approaches to rationally design small molecules targeting RNA
- Approaches to assess target modulation and target validation in cells
The Fine Print
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