Avoiding PAINS (Pan-Assay Interference Compounds) (Free Preview)
Increasingly accessible to academic researchers, high-throughput screening (HTS) is one of the best ways to discover starting points for new chemical probes and first-in-class drug candidates. However, researchers new to HTS do not often appreciate how readily this technology furnishes artefacts (Pan Assay Interference Compounds or PAINS) that can distract and mislead. Join Jonathan Baell as he shares some tips on how to avoid the dead ends of drug discovery.
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