Chemistry of Longevity: Rapamycin's Secret Past and Potential for a Longer Life

September 22, 2016

Carved stone heads on Easter Island

The FDA approved drug rapamycin has been found to delay aging and increase lifespan in diverse laboratory organisms, including yeast, nematodes, fruit flies, and mice.  Although the mechanisms by which rapamycin achieves these remarkable effects are still being elucidated, attention is now turning toward translational applications and studies aimed at determining whether these benefits can be obtained outside of the laboratory.

What You Will Learn

  • Aging is a modifiable biological process; it can be accelerated and delayed through interventions
  • Rapamcyin is a drug that has been shown to delay aging in evolutionarily diverse laboratory organisms
  • Companion dogs offer an outstanding opportunity to begin translating work with rapamycin and other interventions that promote healthy aging from the lab to the clinic

Additional Resources

The Fine Print

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Matt Kaeberlein
University of Washington

­­­­­­­­­­­­­­­­­­­­­­­­­Bethany Halford
Chemical & Engineering News

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