Matthew Disney, a native of Baltimore, Maryland, received his early schooling in the Baltimore Catholic School System, his B.S. from the University of Maryland, and his Ph.D. from the University of Rochester. He is currently a Professor in the Department of Chemistry at The Scripps Research Institute. His laboratory is focused on understanding RNA-ligand interactions, and using this information to rationally design small molecules that modulate and study RNA function or toxicity from only sequence. His laboratory has recently reported success targeting RNA repeat expansions that cause incurable genetic disorders and various non-coding RNAs involved in cancer.