Victor Guarino, Ph.D., has worked in the Pharmaceutical Candidate Optimization (PCO) department at Bristol-Myers Squibb (BMS) since 2004. Guarino originally joined BMS in the Discovery Pharmaceutics group within the PCO department, but has since transitioned to the Metabolism and Pharmacokinetics group within the PCO department. In addition, Guarino continues to provide a general prodrug consulting role across the Drug Discovery organization at BMS where he helps Medicinal Chemists in the design and evaluation of prodrugs.
Guarino received his doctorate from the Department of Pharmaceutical Chemistry at the University of Kansas working under Professor Valentino J. Stella. His doctorate work with Professor Stella represents the first published effort specifically aimed at establishing sulfenamides as novel prodrugs for drugs that contain weakly-acidic NH-acid functionalities (e.g., amides, ureas, etc.).