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John P. Overington

John P. Overington

John studied chemistry at the University of Bath, United Kingdom and continued his studies for a PhD at Birkbeck College, University of London, working on developing software for automated protein modeling, and subsequently sequence-structure comparison methods. John then moved to the laboratories of Pfizer at Sandwich, United Kingdom, where his responsibilities grew to cover structural biology, molecular modeling and chemo-informatics. Subsequently, John took a position at Inpharmatica, where he led the chemo-genomics technology group. John has led the development of many novel databases and algorithms applied to human health research, and explored some of the fundamental reasons for the apparently limited target space for drugs. Most recently, John has moved to the EMBL-EBI to place these databases in the public domain on an open access basis, and to develop data-mining approaches to aid in the target and lead discovery, and lead optimization processes.