Bruce H. Lipshutz
Bruce Lipshutz took his Ph.D. from Yale in 1977 with Harry Wasserman, and then did a two year postdoctoral stint with E. J. Corey at Harvard. He began his professorial career at the University of California, Santa Barbara, in 1979, where today he continues as Professor of Chemistry.
Much of his career has been focused on developing new reagents and technologies that have broad appeal in the synthetic community, many of which are now, or will soon be, commercially available (e.g., SEM-Cl, “Higher Order Cuprates”, “Cuprate-in-a-Bottle”, DCAD, “Copper Hydride-in-a-Bottle”, Ni/C, Cu/C, PTS, TPGS-750-M, etc.). The group’s efforts have, in part, shifted with an emphasis on “green chemistry”. Thus, there is ongoing development of a mix of methods in heterogeneous catalysis, including newly developed mixed metal-supported cross-coupling reagents, and homogeneous catalysis. The latter focuses on micellar catalysis to effect transition metal-catalyzed cross-couplings in water at room temperature, with an accent on development of new “designer surfactants.” Also being actively pursued are projects in total or partial synthesis of biaryls that possess axial chirality (e.g., the A-B biaryl section of vancomycin, and the antimalarial korupensamines and related targets), and syntheses associated with, and analogs derived from, coenzyme Q10.