Patrick Sexton obtained his B.Sc. (Hons) Pharmacology and Ph.D. degrees from the University of Melbourne, Australia. Dr. Sexton has made a significant impact in the fields of pharmacology and translational science. He is a leading international researcher in the field of G protein-coupled receptors (GPCRs). His research crosses industry and academic boundaries through elucidation of fundamental biology and the intersection of this with drug-receptor interactions. He has contributed to the understanding of the distribution of receptors, the structural interface between peptide ligands and receptors, GPCR structure elucidation by cryo-EM, modulation of receptors by accessory proteins, detection and quantification of small-molecule allosteric drug effects, and biased agonism. He has received major awards for his research including the GSK Award for Research Excellence, the Vane Medal (British Pharmacological Society), ASCEPT Lecturer Award and Rand Medal (Australasian Society for Clinical and Experimental Pharmacologists and Toxicologists) and the Senior Plenary Award of the Endocrine Society of Australia.
Dr. Sexton has published 290 articles in peer-reviewed journals, including Nature, Cell, Mol Cell, Nature Chem Biol, Nature Commun, Nature Rev Drug Discov, Nature Rev Mol Cell Biol, J Clin Invest, PNAS and many ACS journals including JACS, ACS Pharmacol Transl Sci, ACS Chem Biol, ACS Chem Neurosci, Biochemistry, Chem Reviews, J Chem Info Mod, J Med Chem.