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Lei Zhang

Lei Zhang

Lei Zhang received his B.S. in chemistry at Peking University in China and then carried out his graduate research in organic chemistry at Stanford University with focus on the total synthesis of natural products and novel transition-metal catalyzed cycloadditions. After receiving his Ph.D. in 2002, he accepted a position as a research scientist at Pfizer Inc. and he is currently a senior principal scientist within neuroscience medicinal chemistry.  He has worked on discovery projects across various disease areas, e.g. Alzheimer’s diseases (AD), Schizophrenia, and Parkinson’s disease, and advanced multiple compounds into the clinic.  In addition to his responsibilities as chemistry leader in drug discovery projects, he ventured into the realm of novel PET ligand development by leading the effort of the PET discovery core within neuroscience in 2009. Since then, he has established a streamlined CNS PET ligand discovery process that successfully delivered PET ligands for a number of programs across different target types (e.g. GPCRs, enzymes, kinases).