Opportunities and Challenges in Using Advanced 21st Century Toxicity Testing and Risk Assessment Methods in a Modernized TSCA

Congress is on the verge of modernizing the now 40-year old Toxic Substances Control Act (TSCA). While the provisions of the new legislation are yet to be finalized, there’s no doubt that the new 21st century technologies and approaches for determining toxicity, bioactivity and exposure will be needed to fulfill the requirements for priority setting and safety determinations.  While considerable progress has been made in developing the 21st century approaches and demonstrating their potential utility, additional focus will be needed to enable regulatory use in a modernized TSCA.

On February 8, 2016, a colloquium was jointly organized by the American Chemical Society (ACS) and the American Chemistry Council (ACC).  In this colloquium, presenters outlined opportunities for utilizing these methods in a new TSCA and discussed opportunities for enhancing the confidence in use of these methods.

Program and Presentation Slides

See links to presentation slides below.

Moderated by Dr. Jack Fowle (ACS Committee on Environmental Improvement)

3:30 – 3:40—Opening Remarks: Dr. Tom Connelly (ACS) and Honorable Cal Dooley (ACC)

3:40 – 3:50—Dr. Rick Becker (ACC): Overview of the Opportunities for Using Advanced 21st Century Methods in a Modernized TSCA

3:50 – 4:10—Dr. Barbara Wetmore (ScitoVation): Priority Setting in the 21st Century: Integrating High-Throughput Toxicity Testing with Exposure

4:10 – 4:30—Dr. John Wambaugh (EPA Office of Research and Development.): Advances in Exposure Science    

4:30 – 4:50—Dr. Kevin M. Crofton (EPA Office of Research and Development.): Current Applications and Future Directions for 21st Century Toxicity Testing and Risk Assessment  

5:00 – 5:30—Panel Perspectives and Discussion:  Moderated by Dr. Jack Fowle and including Dr. Kate Willett (HSUS) and Dr. Grace Patlewicz (EPA Office of Research and Development.) and all speakers

5:30—Closing Remarks: Dr. Jack Fowle

5:30 – 6:30—Reception

Presentation Slides (includes audio)