Azelaic acid, formally nonanedioic acid, is a white crystalline solid with a melting point of 106.5 °C. It occurs naturally in grains such as wheat, rye, and barley and is produced industrially by ozonolyzing oleic acid. It is used topically to treat acne and rosacea. Some plants release azelaic acid as a "distress flare" to signal cells to activate their defenses against attacking pathogens.
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