Carfilzomib

December 10, 2012

Carfilzomib, a selective proteasome inhibitor, is marketed by Onyx Pharmaceuticals under the name Kyprolis. FDA approved the epoxomicin derivative in July 2012 for treating patients with relapsed, refractory multiple myeloma. Work by C. M. Crews and co-workers at Yale University led directly to the development of carfilzomib.

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