Mupirocin is a monoxycarbolic acid antibiotic. It consists of a mixture of pseudomonic acids that are produced by the Gram-negative bacterium Pseudomonas fluorescens. More than 90% of the mixture is pseudomonic acid A (shown), which was isolated, purified, and characterized by A. T. Fuller and co-workers in 1971. First marketed by GlaxoSmithKline under the trade name Bactroban, mupirocin is now also a generic topical drug prescribed for human and veterinary use. In low concentrations, mupirocin is a bacteriostat. At higher levels, it is a bactericide that is effective against Gram-positive bacteria, including MRSA.
Learn more about this molecule from CAS, the most authoritative and comprehensive source for chemical information.
Stay Ahead of the Chemistry Curve
Learn how ACS can help you stay ahead in the world of chemistry.