Molecule of the Week

Coenzyme A

July 20, 2009

Coenzyme A is a cofactor in enzymatic acyl transfer reactions. It participates in the biosynthesis and oxidation of fatty acids and the oxidation of pyruvate in the citric acid cycle. It was discovered by Nobel laureate Fritz Lipmann in 1945. A conjugate of coenzyme A with RNA was recently reported by David R. Liu and co-workers at Harvard.



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