Molecule of the Week

Dihydroxyacetone phosphate

May 21, 2012

Dihydroxyacetone phosphate (DHAP) is a central player in the metabolism of glucose: It is one of the breakdown products of fructose 1,6-bisphosphate. It also occurs in the Calvin reductive pentose phosphate cycle as one of the products of the NADPH reduction of 1,3-bisphosphoglycerate. DHAP has been used as a three-carbon synthon in the aldolase-mediated synthesis of carbohydrate derivatives.

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