Molecule of the Week

Regadenoson

March 12, 2012

Regadenoson is a coronary vasodilator sold under the trade names Lexiscan (Astella Pharma) and Rapiscan (GE Healthcare). It is an adenosine derivative that acts as an A2A adenosine receptor agonist. Recently, M. S. Bynoe and co-workers showed that adenosine released when regadenoson is injected into mice temporarily opens the blood–brain barrier to admit antibodies and polysaccharides.

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