Molecule of the Week

Trichoviridin

December 7, 2009

Trichoviridin, or isonitrin C, is an isonitrile antibiotic with an unusual highly functionalized cyclopentane ring that contains two reactive epoxide substituents. It is isolated from Trichoderma species of soil-borne fungi. D. F. Taber and H. Yu reported its total synthesis in 1999. Trichoviridin and other Trichoderma metabolites have been used to control crop pathogens.