Nakadomarin A

May 07, 2012
Image of Nakadomarin A 3D Image of Nakadomarin A

Nakadomarin A is a sea sponge alkaloid that contains an unusual partially saturated azocine (azacyclooctatetraene) ring. It is also the only member of the manzamine alkaloid family to contain a furan ring. Nakadomarin A shows anticancer, antifungal, and antibacterial activity, but because only tiny amounts exist in nature, an efficient lab synthesis is necessary. A key step of its synthesis was recently improved by A. H. Hoveyda, R. R. Schrock, and co-workers.

Chemical Abstract Service - a division of ACS

Learn more about this molecule from CAS, the most authoritative and comprehensive source for chemical information.

Molecule of the Week needs your suggestions!

If your favorite molecule is not in our archive, please send an email to motw@acs.org. The molecule can be notable for its current or historical importance or for any quirky reason. Thank you!

Stay Ahead of the Chemistry Curve

Learn how ACS can help you stay ahead in the world of chemistry.