Phenothiazine, a heterocyclic compound that contains ring nitrogen and sulfur atoms, was first made in 1883 when A. Bernthsen fused diphenylamine with sulfur. By 1954, its chemistry was rich enough to be described in Chemical Reviews . Phenothiazine and its derivatives (notably chlorpromazine, or Thorazine) are marketed as antipsychotic and antihistaminic drugs.
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