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ACS News Service Weekly PressPac: October 01, 2014
A novel method for portable detection of potent drugs known as 'bath salts'
"Forensic Electrochemistry Applied to the Sensing of New Psychoactive Substances: Electroanalytical Sensing of Synthetic Cathinones and Analytical Validation in the Quantification of Seized Street Samples"
Despite being outlawed in 2012 in the U.S., the synthetic drugs known as "bath salts" — which really aren't meant for your daily bath — are still readily available in some retail shops, on the Internet and on the streets. To help law enforcement, scientists are developing a novel method that could be the basis for the first portable, on-site testing device for identifying the drugs. They report their advance in the ACS journal Analytical Chemistry.
Craig E. Banks, in collaboration with Oliver Sutcliffe, notes that the high-inducing substances in bath salts, which are synthetic cathinones that also go by "plant food," "glass cleaner" and a number of other innocuous-sounding names, are derived from a stimulant in a plant called khat. The plant is found on the Arabian peninsula and East Africa. The drugs' effects are similar to those of amphetamines. Users reportedly feel an initial sense of euphoria, but this is followed by unpredictable and potentially dangerous effects, including seizures and hallucinations. Since bath salts first appeared in Europe and the U.S. more than four years ago, alarming reports emerged of users becoming violent. Tens of thousands of emergency room visits and several deaths have been attributed to the substances. Scientists have been working successfully on different techniques to identify the synthetic drugs, but the methods aren't portable. One group turned to an electrochemical approach, which can be adapted for in-the-field use, but their technique involved toxic mercury as the electrode. Banks' team wanted to find a better, safer way to perform bath salts "fingerprinting."
Using more environmentally friendly, mercury-free electrodes, the researchers developed a low-cost, disposable and rapid platform that could someday be used in a handheld sensor for detecting bath salts. They validated their technique using samples that were obtained from Internet vendors. The accuracy of their results matched that of established methods.