How to Beat Spicy Pepper Heat (Hint: Milk Isn't the Best)

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Reactions Science Videos | October 09, 2020

Maybe you’ve heard that milk is the perfect way to extinguish that spicy food burn--but what if you can’t drink milk? This week our lactose-intolerant host, Sam, eats serrano peppers alongside lactose-tolerant George and they both try to find something that quenches the burn. Spoiler alert: One of them does a heck of a lot better than the other.

Sources:
Capsaicin

The chemistry of a chili

Understand spiciness: mechanism of TRPV1 channel activation by capsaicin

Capsaicin, Nociception and Pain

Capsaicin: Risks and Benefits

The paradoxical role of the transient receptor potential vanilloid 1 receptor in inflammation.

Integrative Approaches to Pain Management

The cool science of hot peppers

Unraveling the mystery of capsaicin

Capsaicin: Current Understanding of Its Mechanisms and Therapy of Pain and Other Pre-Clinical and Clinical Uses

Capsaicin may have important potential for promoting vascular and metabolic

Capsaicin chemical structure

Harnessing the Therapeutic Potential of Capsaicin and Its Analogues in Pain and Other Diseases

Capsaicin: An Uncommon Exposure and Unusual Treatment

Antimicrobial and Anti-Virulence Activity of Capsaicin Against Erythromycin-Resistant, Cell-Invasive Group A Streptococci

Perceptual and Affective Responses to Sampled Capsaicin Differ by Reported Intake

Personality factors predict spicy food liking and intake

Capsaicin Improves Glucose Tolerance and Insulin Sensitivity Through Modulation of the Gut Microbiota-Bile Acid-FXR Axis in Type 2 Diabetic db/db Mice.

Learning to Like Spicier Food

Why some people can tolerate the world’s hottest pepper

Advice on building tolerance (from a non-expert)

Are People Born With A Tolerance For Spicy Food?

Serious Eats on how to build your spicy foods tolerance

A randomized, double-blind, positive-controlled, 3-way cross-over human experimental pain study of a TRPV1 antagonist (V116517) in healthy volunteers and comparison with preclinical profile.

Chili peppers for weight loss

Anti-obesity Effect of Capsaicin in Mice Fed with High-Fat Diet Is Associated with an Increase in Population of the Gut Bacterium Akkermansia muciniphila

Milk for chili peppers (Kool Aid?)

Do Genetics Shape Your Spicy-Food Threshold?

Ask the doctor: How does hot pepper cream work to relieve pain?

Why do some like it hot? Genetic and environmental contributions to the pleasantness of oral pungency

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