The deadly bacteria can linger in biological treatment ponds and elsewhere—but how far can airborne pathogenic strains of legionellae travel?

Gold nanoparticles are potentially useful in medical diagnostics, but their cytotoxicity must also be considered. Also discussed: Cellular imaging using plasmon bands of gold nanorods.

Cystic fibrosis patients could soon benefit from breakthrough small-molecule drugs that treat their underlying disease instead of just their symptoms.

Rigid tricyclic scaffolds that can function as peptide backbone mimetics can be synthesized in four steps from bicyclic 2-pyridones. The substituents can be varied to fine-tune biological response.

This polymeric 3-D model may help decrease the efficacy gap that exists between in vitro testing of potential drugs on cancer cells grown in 2-D monolayers and in vivo testing on actual 3-D tumors.

In vivo-generated HOCl and N-chloramines are a two-edged sword: They kill invading pathogens, but they can also damage tissue. This study identifies plasma proteins susceptible to thiol oxidation by the two agents.