MOLECULE OF THE WEEK

You can make me in base but not in acid.
What molecule am I?

Aldosterone Zapper
These mitochondrial benzimidazole cytochrome P450 aldosterone synthase (CYP11B2) inhibitors should lower circulating plasma aldosterone levels. 

ACS Medicinal Chemistry Letters

Better Vaccine Adjuvants
The authors describe the development of safe, efficient nanoparticle-based vaccine adjuvants that can control the balance of immune responses.

Bioconjugate Chemistry

Anticancer Ru(II) Complexes
Varying the ligands in organoruthenium(II) complexes provides insight into their activity against ovarian cancer and osteosarcoma cell models.

Journal of Medicinal Chemistry