C&EN Webinar

Approaches to Uncooperative Drugs in In Vitro Transporter Research

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On-demand virtual event


Biological & Medicinal Chemistry

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In vitro drug transporter data is critical for understanding drug-drug interaction potential, but this data is only useful if conclusions can be drawn. Researchers are confronted with practical challenges associated with compounds that are unstable, sticky or insoluble, resulting in convoluted or inconclusive results.

Three interesting transporter case studies will be presented, each highlighting a creative solution to explore perplexing initial results and generate useful data, despite problematic physicochemical characteristics of the drugs involved.


Joanna Barbara, PhD

ADME Research Site Head, BioIVT

ACS Institute

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