Pharmacology for Chemists

The interface between a Biologist and Medicinal Chemist are at the heart of a drug discovery program and it is critical that there be mutual understanding of the different disciplines involved. Pharmacology is the chemical control of physiology, but how can physiology be expressed in chemical terms?

When drugs interact with living systems they can present different profiles of activity in the body. Join Terry Kenakin, Professor of Pharmacology at the UNC School of Medicine as he illustrates how Pharmacology uses descriptive and predictive data to extend the snapshot of activity for a drug in a test system with scales that can predict drug activity in a full range of physiological systems. Register now to learn the basics of the drug discovery process and the key issues of system-independent properties like efficacy and affinity, in making a therapeutic drug that can better guide molecule candidate selection and reduce attrition.

This ACS Webinar is moderated by Bryan Tweedy of the American Chemical Society and co-produced by the ACS Office of Career and Professional Education.

What You Will Learn

• How chemicals affect physiology and the properties that are required to modify drug efficacy and affinity
• How the data coming from pharmacological assays are used for structure-activity modification
• The current landscape of drug targets and the process of how to validate those targets for therapeutic advantage and how the mechanisms of actions of various drugs uniquely modify according to disease

Meet The Experts

• Terry Kenakin, Professor of Pharmacology, UNC School of Medicine
• Bryan Tweedy, Assistant Director, ACS Education, Office of Career and Professional Education, American Chemical Society