Designing around Structural Alerts in Drug Discovery

ACS Webinars

Contemporary drug design is a challenging process that requires the holistic assimilation of multiple parameters in order to identify a candidate molecule.

Join Vice President Nick Meanwell of BMS Research and Early Development as he provides a synopsis of structural alerts in drug discovery. During this free interactive Friday broadcast, discover known alerts and their associated issues as well as the underlying mechanistic organic chemistry that will allow you to implement strategies to avoid potential problems in the design process.

This ACS Webinar is moderated by Head of Drug Metabolism and Pharmacokinetics, Deepak Dalvie of Crinetics Pharmaceuticals and is co-produced with the ACS Division of Medicinal Chemistry, American Association of Pharmaceutical Scientists, and ACS Publications.

What You Will Learn

  • The identity of structural alerts that have been associated with problems in drug discovery and development
  • The fundamental mechanistic organic chemistry subtending structural alerts that are subject to bioactivation
  • Strategies to design around structural alerts


Nick Meanwell,
Vice President,
Bristol Myers Squibb Research and Early Development

Deepak Dalvie
Head of Drug Metabolism and Pharmacokinetics,
Crinetics Pharmaceuticals

Co-Produced With

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