Cortisone (shown) and its close cousin prednisone (with an additional double bond) are widely used anti-inflammatory agents, but their use must be monitored carefully because they can suppress the immune system. Cortisone was identified in the 1930s by Edward C. Kendall at the Mayo Clinic, who shared the 1950 Nobel Prize for physiology or medicine for his work. Prednisone was developed in the 1950s by Arthur Nobile and co-workers at Schering.
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