AbbVie and Enanta Pharmaceuticals
Mavyret® is a direct-acting antiviral, treats chronic hepatitis C in adults and children and meets the requirements of efficacy and widespread availability to advance the goal of eradicating the infection, which affects an estimated 58 million people worldwide.
Awardees: Vusi Moyo, Rolf Wagner, John Randolph, Mark Matulenko, Warren Kati, Keith McDaniel, Pamela Donner, Yat Sun Or, Guoqiang Wang ,Jun Ma, Seble Wagah, Russell Cink, Jeffrey Kallemeyn, David Hill, Westin Morrill, Timothy Towne, Matthew Pelc, Kenneth Engstrom, Kirill Lukin, Michael Abrahamson, Clifford Mitchell, Shuang Chen, Nandakishor Nere, Moiz Diwan, Jean-Christophe Califano, Shashank Shekhar, Brian Kotecki, Mathew Mulhern, Daniel Mack, Jordan Stobaugh, Alessandra Mattei, Laurie Mlinar, Steven Elmore, and Phil Kim.
Honeywell
Solstice® LBA is a non-ozone-depleting, non-flammable, hydrofluoroolefin (HFO) blowing agent with an ultra-low global warming potential of 1, 99.9% lower than that of HFC blowing agents. It enables highperformance foam insulation and safety in use with a reduced environmental impact.
Awardees: Rajiv Singh, Michael Van Der Puy, Hang Pham, Ryan Hulse, Haiyou (Hugh) Wang, Daniel Merkel, Joshua Close, David Williams, Mary Bogdan, Jim Ling, Thomas Isberg, and Laura Reinhard.
Incyte
Jakafi® is the first medication to treat rare blood cancers and chronic and acute graft-versus-host disease by reducing overactive signaling that involves proteins called Janus kinases and results in excessive production of red blood cells and inflammation.
Awardees: Stacey Shepard, James D. Rodgers, Thomas P. Maduskuie, Mei Li, Laurine G. Galya, Peggy A. Scherle, Maryanne Covington, Yvonne Lo, Kris Vaddi, Yanlong Li, Gregory Hollis, Jack Shi, Swamy Yeleswaram, Ryan McGee, Yong Ni, Trupti Sheth, Bhavnish Parikh, Jiacheng Zhou, Pingli Liu, David J. Meloni, Yongchun Pan, Lixin Shao, Nikoo Falahatpisheh, Haisheng (Jason) Wang, Sergio C. Nanita and Catalina Loveman*
Merck and Co. Inc.
Bridion® is approved in 95+ countries for reversal of the effects of certain neuromuscular blocking agents in adults undergoing surgery. It binds these agents, reducing the amount of active drug.
Awardees: Jonathan Bennett, David Rees, Ronnie Palin, Jamie McCabe Dunn, Yu He, Michael Ward, Ming-Qiang Zhang, David Thaisrivongs, Angela Spartalis, Rebecca Ruck, Marguerite Mohan, David Lamberto, Nadine Kuhl, Bharath Krishnamurthi’d Gauthier, and Yang Cao.
Vertex Pharmaceutical
Trikafta® takes a novel approach to treatment of cystic fibrosis in adults and children by combining three active compounds to target and correct for underlying genetic defects that cause disease in 90% of people living with this condition.
Awardees: Sabine Hadida, Mark Miller, Vito Melillo, David Siesel, Jeremy Clemens, Billie Kline, Samantha Guido, Jason McCartney, Fabrice Pierre, Jinglan Zhou, Alex Abela, Hari Khatuya, Paul Angell, Bérénice Lewandowsk, Yanwei Zhang, Johnny Uy, Timothy Cuman, and Mark Bunnage
ViiV Healthcare
RUkobia™ is a first-in-class attachment inhibitor that prevents HIV-1 from interacting with host immune cells, is an antiretroviral therapy for people who are living with multidrug-resistant HIV-1 and whose treatment regimens are otherwise failing.
Awardees: Timothy Connolly, Richard Colonno, Martin Eastgate, David Conlon, Nicholas Meanwell, Peter Timmins, Jonathan Brown, Yasutsugu Ueda, Tao Wang, Pin-fang Lin, Chung-Pin Herman Chen, John Kadow, and Max Lataillade