May 03, 2011
Image of Bupropion 3D Image of Bupropion

Bupropion, whose best known trade name is Wellbutrin, is an antidepressant that is believed to inhibit norepinephrine and dopamine reuptake. It is an atypical antidepressant because it does not have a tricyclic structure and is not a selective serotonin reuptake inhibitor. Bupropion is also used as an aid to stop smoking and to combat anxiety, sexual dysfunction, and obesity. [Taken from Wikipedia—Ed.]

MOTW update:
December 19, 2022

Bupropionis an antidepressant and antianxiety drug. Dextromethorphan2, the Molecule of the Week for January 6, 2014, is a commonly used cough suppressant. Now the two have been combined by Axsome Therapeutics (New York City) into a pill for treating major depressive disorder. Dextromethorphan is believed to modulate neurotransmission of glutamate, which likely plays a role in depression. In addition to its antidepressant properties, bupropion increases dextromethorphan levels in the blood.

1. CAS Reg. No. 34911-55-2.
2. CAS Reg. No. 125-71-3.

Chemical Abstract Service - a division of ACS

Learn more about this molecule from CAS, the most authoritative and comprehensive source for chemical information.

Molecule of the Week needs your suggestions!

If your favorite molecule is not in our archive, please send us a message. The molecule can be notable for its current or historical importance or for any quirky reason. Thank you!

Stay Ahead of the Chemistry Curve

Learn how ACS can help you stay ahead in the world of chemistry.