Bupropion

May 02, 2011
Image of Bupropion 3D Image of Bupropion

Bupropion, whose best known trade name is Wellbutrin, is an antidepressant that is believed to inhibit norepinephrine and dopamine reuptake. It is an atypical antidepressant because it does not have a tricyclic structure and is not a selective serotonin reuptake inhibitor. Bupropion is also used as an aid to stop smoking and to combat anxiety, sexual dysfunction, and obesity. [Taken from Wikipedia—Ed.]

MOTW update:
December 19, 2022

Bupropionis an antidepressant and antianxiety drug. Dextromethorphan2, the Molecule of the Week for January 6, 2014, is a commonly used cough suppressant. Now the two have been combined by Axsome Therapeutics (New York City) into a pill for treating major depressive disorder. Dextromethorphan is believed to modulate neurotransmission of glutamate, which likely plays a role in depression. In addition to its antidepressant properties, bupropion increases dextromethorphan levels in the blood.

1. CAS Reg. No. 34911-55-2.
2. CAS Reg. No. 125-71-3.

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