January 14, 2008
Image of Cisplatin 3D Image of Cisplatin

Cisplatin was first identified in 1845; it was originally of interest during the development of coordination theory. At that time, it was called Peyrone’s salt or Peyrone’s chloride, after its discoverer, Michel Peyrone. In the mid-1960s, Cisplatin’s antitumor activity was demonstrated, and it has served as the gold standard (should that be “platinum standard”?) against which newer drugs are compared. Cisplatin is probably best known for its role in helping Tour de France winner Lance Armstrong fight testicular cancer. The trans isomer does not exhibit a similar pharmacological effect.

Related Article: "Sound Science", Chemical & Engineering News, April 7, 2014

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