Fluocinonide is a generic glucocorticoid steroid that has been used for many years in topical anti-inflammatory preparations to treat skin conditions such as eczema and dermatitis. It is or has been available under many trade names in cream, ointment, or liquid formulations. It is also prescribed by veterinarians to treat skin allergies in dogs.
The synthesis of fluocinonide was first reported in a 1959 British patent assigned to Olin Mathieson. US patents to Syntex and Pharmaceutical Research Products followed in 1964–65.
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