Pafuramidine

December 19, 2011
Image of Pafuramidine 3D Image of Pafuramidine

Pafuramidine, a US FDA–designated orphan drug, has been tested against the parasitic trypanosome disease human African trypanosomiasis ( sleeping sickness). Pafuramidine reached Phase III clinical trials for sleeping sickness; but in 2008, it was pulled because it produced liver toxicity and renal insufficiency. New preliminary clinical trials show that pafuramidine is effective against pneumocystitis pneumonia with relatively few side effects.

Chemical Abstract Service - a division of ACS

Learn more about this molecule from CAS, the most authoritative and comprehensive source for chemical information.

Molecule of the Week needs your suggestions!

If your favorite molecule is not in our archive, please send us a message. The molecule can be notable for its current or historical importance or for any quirky reason. Thank you!

Stay Ahead of the Chemistry Curve

Learn how ACS can help you stay ahead in the world of chemistry.