Medicinal chemistry is a stimulating field as it links many scientific disciplines and allows for collaboration with other scientists in researching and developing new drugs.
Medicinal chemists apply their chemistry training to the process of synthesizing new pharmaceuticals. They also improve the processes by which existing pharmaceuticals are made. Medicinal chemists are focused on drug discovery and development and are concerned with the isolation of medicinal agents found in plants, as well as the creation of new synthetic drug compounds. Most chemists work with a team of scientists from different disciplines, including biologists, toxicologists, pharmacologists, theoretical chemists, microbiologists, and biopharmacists. Together, this team uses sophisticated analytical techniques to synthesize and test new drug products and to develop the most cost-effective and environmentally friendly means of production.
Generally, pharmaceutical companies prefer to hire people with research experience, advanced degrees (especially in organic chemistry), and at least two years of post-doctoral experience. Most chemists in traditional research careers are Ph.D. chemists, while chemists with B.S. degrees generally serve as research technicians. You can place yourself in a competitive position by getting as much industrial experience as possible, with a strong background in organic chemistry and biochemistry. A number of universities have medicinal chemistry departments, often associated with biological chemistry, pharmaceutical chemistry, pharmacology, or pharmacy programs.
Medicinal chemistry offers a wide variety of lab opportunities in pharmaceutical, biotechnology, and medical device companies. Most chemists use their research skills to formulate, produce, characterize, and analyze new compounds for specific applications. However, each lab environment is unique in regards to daily activities and career opportunities. In some cases, laboratory work is not always required, for example, when reviewing drug applications at the FDA.
Many medicinal chemists start out in the lab and then move on to other laboratory career such as process chemistry, formulation chemistry, quality control or quality assurance. They may also move to nonlaboratory careers such as regulatory affairs, intellectual property (patents), project management, or technology transfer.
The outlook for this field is mixed due to changing economy and government health care reform regulations. Pharmaceutical companies have been downsizing their research labs, merging with other companies, and outsourcing research for many years. Some outsourcing has also taken place overseas, reducing opportunities for domestic pharmaceutical jobs. Small companies and contract research firms are some of the more promising places for employment in medicinal chemistry.
Medicinal chemists must enjoy varied activities and be excited about exploring the unknown. A good imagination and persistence are also two important qualities to have when considering a career in medicinal chemistry. Being a team player with good written and verbal communication skills are invaluable assets when interacting with scientists from other disciplines. Knowing that your work is helping to improve human health and reduce suffering is a strong motivating factor for many in this field.
Pharmaceutical companies have been downsizing their research labs or merging with other companies. Meanwhile, some government agencies are looking for chemists to fill nonlaboratory chemistry positions. Some outsourcing has also taken place overseas, reducing opportunities for domestic pharmaceutical jobs.