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November 23, 2020
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Happy Thanksgiving! If you are like many of us, sweet potatoes (aka yams) are one of the highlights of your Turkey Day meal. The aroma of a casserole baking in the oven adds to that comfort-food feeling.

A chemist would naturally ask, “Why do roasting or baking sweet potatoes smell so good?” Ola Lasekan* and Li Shing Teoh at University Putra Malaysia (Serdang), identified 29 aroma compounds in roasting white yam (Dioscorea rotundata)1. Among them, the two that had the highest odor activity factors were 2-acetylfuran (2AF, aka 2-furyl methyl ketone) and 2-acetylpyrrole (2AP, aka 2-pyrrolyl methyl ketone).

According to the authors, 2AF “elicited an almond-like note” whereas 2AP had “a popcorn-like note”. The aromas emitted by the other components, mostly furans, pyrroles, and pyrazines, were given labels such as “toasty”, “caramel”, “chamomile flower–like”, and “smoky”.

The focus of this study was to identify the aroma compounds that contribute to the potatoes’ antioxidant properties. Using an established test based on substances’ ability to inhibit the oxidation of hexanal, the authors found that the pyrrole-containing aroma components were substantially superior antioxidants to the furans and especially the pyrazines.

A glance at the hazard information tables shown here might give you pause. 2AF in particular looks as if it might kill you as you’re enjoying the holiday. But rest assured that these, like many other odorous substances, are detectable in air at very low concentrations.

So, this Thanksgiving Day, while you’re watching the virtual Macy’s parade and NFL football games, take satisfaction that some of the food aromas you’re inhaling add to your antioxidant supply.

1. Full disclosure: Dioscorea spp. are “true yams”, as opposed to the orange-colored sweet potatoes (Convolvulaceae spp.) that some Americans call yams. The baking and roasting aromas of both yam genera contain 2AF and 2AP.

2-Acetylfuran hazard information

Hazard class*Hazard statement
Flammable liquids, category 4

H227—Combustible liquid

Acute toxicity, oral, category 2H300—Fatal if swallowedChemical Safety Warning
Acute toxicity, dermal , category 3H311—Toxic in contact with skinChemical Safety Warning
Serious eye damage/eye irritation, category 1H318—Causes serious eye damageChemical Safety Warning
Acute toxicity, inhalation, category 2 H330—Fatal if inhaledChemical Safety Warning

*Globally Harmonized System of Classification and Labeling of Chemicals.  
Explanation of pictograms.

2-Acetylpyrrole hazard information

Hazard class*Hazard statement
Acute toxicity, oral, category 4H302—Harmful if swallowedChemical Safety Warning
Skin corrosion/irritation, category 2H315—Causes skin irritationChemical Safety Warning
Specific target organ toxicity, single exposure, respiratory tract irritation, category 3H335—May cause respiratory irritationChemical Safety Warning

*Globally Harmonized System of Classification and Labeling of Chemicals.  
Explanation of pictograms.

2-Acetylfuran fast facts

CAS Reg. No.1192-62-7
Ethanone, 1-(2-furanyl)-
Empirical formulaC6H6O2
Molar mass110.11 g/mol
AppearanceYellow to brown liquid or solid
Melting range26–33 ºC
Boiling point175 ºC
Water solubility Very slight

2-Acetylpyrrole fast facts

CAS Reg. No.1072-83-9
Ethanone, 1-(1H-pyrrol-2-yl)-
Empirical formulaC6H7NO
Molar mass109.13 g/mol
AppearanceWhite to beige crystals or powder
Melting point90.0–90.5 ºC
Water solubility 274 g/L
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Learn more about this molecule from CAS, the most authoritative and comprehensive source for chemical information.

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