Propranolol is an early nonselective beta blocker used primarily to treat high blood pressure, angina pectoris, and other cardiovascular conditions. It was developed in the 1950s by J. W. Black at ICI (now AstraZeneca); he received a share of the 1988 Nobel Prize in physiology or medicine for his work. Of propranolol’s two optical isomers, the (S)-enantiomer is the more bioactive.
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