May 26, 2008
Image of Cycloguanil

Cycloguanil was first observed in 1951 as a metabolite of the antimalarial drug chlorguanide; it also has shown activity against malaria. Because traditional antimalarials are becoming ineffective against new strains of the malarial protozoan Plasmodium falciparum, renewed efforts are underway to develop cycloguanil into a commercial drug.

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