August 31, 2010
Image of Sulfanilamide 3D Image of Sulfanilamide

Sulfanilamide was one of the earliest sulfonamide antimicrobials. It was first synthesized in 1908 by P. Gelmo and first used as a chemotherapeutic agent in 1935 by G. Domagk, J. Trefouel, and T. Trefouel. They thought that the drug was a complex sulfonamide; but it was later shown that its metabolite, sulfanilamide, was the true active substance.

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